4,583 research outputs found

    Alien Registration- Haynes, Pearl C. (Auburn, Androscoggin County)

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    https://digitalmaine.com/alien_docs/31101/thumbnail.jp

    Alien Registration- Wortman, Pearl C. (Mars Hill, Aroostook County)

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    https://digitalmaine.com/alien_docs/34131/thumbnail.jp

    Commodity, Firmness and Mud: Some Personal Observations on Building with Adobe

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    Mortgagability of Rents, Profits, Appointment of Receivers

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    The prevailing view, and the one which has always been adopted in Washington, is that a mortgage upon realty creates merely a lien thereon and does not pass title thereto, either before or after condition broken, Hyde v. Heller; Dane v. Dansel; Fischer v. Woodruff; this view being codified by an act of the territorial legislature of 1869 providing that A mortgage of real property shall not be deemed a conveyance so as to enable the owner of the mortgage to recover possession of the real property, without a foreclosure and sale according to law

    Letter, n.d., from Pearl C. Bates to Eva Jessye

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    1 page, Bates was an old friend of Jessye

    Thirty Years of New Mexico Architecture Magazine

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    Evidence for Thermally Activated Spontaneous Fluxoid Formation in Superconducting Thin-Film Rings

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    We have observed spontaneous fluxoid generation in thin-film rings of the amorphous superconductor Mo3_3Si, cooled through the normal-superconducting transition, as a function of quench rate and externally applied magnetic field, using a variable sample temperature scanning SQUID microscope. Our results can be explained using a model of freezout of thermally activated fluxoids, mediated by the transport of bulk vortices across the ring walls. This mechanism is complementary to a mechanism proposed by Kibble and Zurek, which only relies on causality to produce a freezout of order parameter fluctuations.Comment: 4 pages, 3 figure

    The Sensitivity of the IceCube Neutrino Detector to Dark Matter Annihilating in Dwarf Galaxies

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    In this paper, we compare the relative sensitivities of gamma-ray and neutrino observations to the dark matter annihilation cross section in leptophilic models such as have been designed to explain PAMELA data. We investigate whether the high energy neutrino telescope IceCube will be competitive with current and upcoming searches by gamma-ray telescopes, such as the Atmospheric Cerenkov Telescopes (ACTs) (HESS, VERITAS and MAGIC), or the Fermi Gamma Ray Space Telescope, in detecting or constraining dark matter particles annihilating in dwarf spheroidal galaxies. We find that after ten years of observation of the most promising nearby dwarfs, IceCube will have sensitivity comparable to the current sensitivity of gamma-ray telescopes only for very heavy (m_X > 7 TeV) or relatively light (m_X < 200 GeV) dark matter particles which annihilate primarily to mu+mu-. If dark matter particles annihilate primarily to tau+tau-, IceCube will have superior sensitivity only for dark matter particle masses below the 200 GeV threshold of current ACTs. If dark matter annihilations proceed directly to neutrino-antineutrino pairs a substantial fraction of the time, IceCube will be competitive with gamma-ray telescopes for a much wider range of dark matter masses.Comment: 7 pages, 3 figures. v2: references added and minor revisions. v3: as published in PRD

    Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2.

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    Poly(ADP-ribose) polymerase-1 (PARP-1) has become an important pharmacological target in the treatment of cancer due to its cellular role as a 'DNA-strand break sensor', which leads in part to resistance to some existing chemo- and radiological treatments. Inhibitors have now been developed which prevent PARP-1 from synthesizing poly(ADP-ribose) in response to DNA-breaks and potentiate the cytotoxicity of DNA damaging agents. However, with the recent discoveries of PARP-2, which has a similar DNA-damage dependent catalytic activity, and additional members containing the 'PARP catalytic' signature, the isoform selectivity and resultant pharmacological effects of existing inhibitors are brought into question. We present here the crystal structure of the catalytic fragment of murine PARP-2, at 2.8 A resolution, and compare this to the catalytic fragment of PARP-1, with an emphasis on providing a possible framework for rational drug design in order to develop future isoform-specific inhibitors
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